a comparison of the effect of honey and vitamin e on sex hormone levels in male wistar rats exposed to noise pollution
نویسندگان
چکیده
background and objectives: noise pollution has a high prevalence among the environmental pollutions and is considered as a teratogenic agent for reproductive system. this study was performed with the purpose of evaluation of the effect of honey and vitamin e on sex hormone levels in male rats exposed to noise pollution. methods: twenty-four adult male rats with the mean weight of 200±20g were randomly divided into 4 groups: 1 (honey+voice), 2 (vitamin e+voice), 3 (voice), and 4 (control). groups 1 and 2 received honey and vitamin e as gavage, in addition to voice; group 3 was only exposed to noise pollution. after 50 days, serum level of hormone in male rats were measured by elisa technique after taking blood from heart. then, the male rats were placed in a cage with female rats of the same breed with a 2:1 ratio. weight and number of embryos from fertilization were assessed. data were analyzed using anova and tukey statistical methods. results: in this study, it was found that the secretion of sex hormones (fsh, lh, and testosterone) impaired under the effect of noise pollution. serum level of testosterone decreased in rats that were under noise stress (p<0.05), and use of honey and vitamin e as antioxidants were modulated the level of this hormone in male rats. noise pollution in male rats increased in the serum level fsh, lh (p<0.05). weight and number of live embryos decreased because of this stress (p<0.05). the use of honey and vitamin e by male rats increased live embryos (p<0.05). conclusion: according to the results of this study, noise pollution has negative effects on the fertility of male rats. also, use of honey and vitamin e increases the fertility in groups exposed to noise pollution.
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عنوان ژورنال:
مجله دانشگاه علوم پزشکی قمجلد ۷، شماره ۵، صفحات ۱-۷
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